产品货号：
GS4424
中文名称：
重组人I-TAC/CXCL11
英文名称：
Recombinant Human I-TAC/CXCL11
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 8.3kDa,a single non-glycosylated polypeptide chain containing 73 amino acids.
储存条件：冷冻（-20℃）
概述
CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36%and 37%amino acid sequence homology with IP-10 and MIG,respectively.It is highly expressed in peripheral blood leukocytes,pancreas and liver.Expression of CXCL11 is strongly induced by IFN-γ and IFN-β,and weakly induced by IFN-α.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3,which with a higher affinity than do the other chemokines for this receptor,CXCL9 and CXCL10.Similar to CXCL10,CXCL11 has been shown to be a chemoattractant for IL-2-activated T-lymphocytes,but not for isolated T-cells,neutrophils or monocytes.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人I-TAC/CXCL11，I-TAC/CXCL11, Human，Recombinant Human I-TAC/CXCL11
储存条件：冷冻（-20℃）
概述
CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36%and 37%amino acid sequence homology with IP-10 and MIG,respectively.It is highly expressed in peripheral blood leukocytes,pancreas and liver.Expression of CXCL11 is strongly induced by IFN-γ and IFN-β,and weakly induced by IFN-α.This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3,which with a higher affinity than do the other chemokines for this receptor,CXCL9 and CXCL10.Similar to CXCL10,CXCL11 has been shown to be a chemoattractant for IL-2-activated T-lymphocytes,but not for isolated T-cells,neutrophils or monocytes.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞97%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10ng/ml. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,100 mM NaCl. |
| 内毒素 | Less than 1 EU/μg of rHuI-TAC/CXCL11 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF |
相关搜索：重组人I-TAC/CXCL11，I-TAC/CXCL11, Human，Recombinant Human I-TAC/CXCL11